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Isolation of anti-CD22 Fv with high affinity by Fv display on human cells
In vitro antibody affinity maturation has generally been achieved by display of mouse or human antibodies on the surface of microorganisms (phage, bacteria, and yeast). However, problems with protein folding, posttranslational modification, and codon usage still limit the number of improved antibodi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1480459/ https://ncbi.nlm.nih.gov/pubmed/16763048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603653103 |
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