Synthesis and characterization of a novel retinylamine analog inhibitor of constitutively active rhodopsin mutants found in patients with autosomal dominant retinitis pigmentosa

Por Yang, Tong, Snider, Barry B., Oprian, Daniel D.
Publicado em 1997

Relocating the active-site lysine in rhodopsin and implications for evolution of retinylidene proteins

Por Devine, Erin L., Oprian, Daniel D., Theobald, Douglas L.
Publicado em 2013

Relocating the active-site lysine in rhodopsin: 2. Evolutionary intermediates

Por Devine, Erin L., Theobald, Douglas L., Oprian, Daniel D.
Publicado no Biochemistry (2016)

Assembly of an Activated Rhodopsin/Transducin Complex in Nanoscale Lipid Bilayers

Por D’Antona, Aaron M., Xie, Guifu, Sligar, Stephen G., Oprian, Daniel D.
Publicado em 2013

Crystal Structure of Recoverin with Calcium Ions Bound to Both Functional EF-Hands

Por Kumar, Ramasamy P., Ranaghan, Matthew J., Ganjei, Allen Y., Oprian, Daniel D.
Publicado no Biochemistry (2015)

Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II

Por Deupi, Xavier, Edwards, Patricia, Singhal, Ankita, Nickle, Benjamin, Oprian, Daniel, Schertler, Gebhard, Standfuss, Jörg
Publicado em 2012

A Highly Conserved Cysteine of Neuronal Calcium-sensing Proteins Controls Cooperative Binding of Ca(2+) to Recoverin

Por Ranaghan, Matthew J., Kumar, Ramasamy P., Chakrabarti, Kalyan S., Buosi, Vanessa, Kern, Dorothee, Oprian, Daniel D.
Publicado em 2013

Structural origins of constitutive activation in rhodopsin: Role of the K296/E113 salt bridge

Por Kim, Jong-Myoung, Altenbach, Christian, Kono, Masahiro, Oprian, Daniel D., Hubbell, Wayne L., Khorana, H. Gobind
Publicado em 2004

Crystal Structure of a Thermally Stable Rhodopsin Mutant

Por Standfuss, Jörg, Xie, Guifu, Edwards, Patricia C., Burghammer, Manfred, Oprian, Daniel D., Schertler, Gebhard F. X.
Publicado em 2007

Functional and Structural Characterization of a (+)-Limonene Synthase from Citrus sinensis

Por Morehouse, Benjamin R., Kumar, Ramasamy P., Matos, Jason O., Olsen, Sarah Naomi, Entova, Sonya, Oprian, Daniel D.
Publicado no Biochemistry (2017)

Low aqueous solubility of 11-cis-retinal limits the rate of pigment formation and dark adaptation in salamander rods

Por Frederiksen, Rikard, Boyer, Nicholas P., Nickle, Benjamin, Chakrabarti, Kalyan S., Koutalos, Yiannis, Crouch, Rosalie K., Oprian, Daniel, Cornwall, M. Carter
Publicado em 2012

Crystal structure of constitutively active rhodopsin: How an agonist can activate its GPCR

Por Standfuss, Jörg, Edwards, Patricia C., D’Antona, Aaron, Fransen, Maikel, Xie, Guifu, Oprian, Daniel D., Schertler, Gebhard F. X.
Publicado em 2011

Low aqueous solubility of 11-cis-retinal limits the rate of pigment formation and dark adaptation in salamander rods

Por Frederiksen, Rikard, Boyer, Nicholas P., Nickle, Benjamin, Chakrabarti, Kalyan S., Koutalos, Yiannis, Crouch, Rosalie K., Oprian, Daniel, Cornwall, M. Carter
Publicado em 2014

Structural Characterization of Early Michaelis Complexes in the Reaction Catalyzed by (+)-Limonene Synthase from Citrus sinensis Using Fluorinated Substrate Analogues

Por Kumar, Ramasamy P., Morehouse, Benjamin R., Matos, Jason O., Malik, Karan, Lin, Hongkun, Krauss, Isaac J., Oprian, Daniel D.
Publicado no Biochemistry (2017)

Preparation of an Activated Rhodopsin/Transducin Complex Using a Constitutively Active Mutant of Rhodopsin

Por Xie, Guifu, D'Antona, Aaron M., Edwards, Patricia C., Fransen, Maikel, Standfuss, Jorg, Schertler, Gebhard F. X., Oprian, Daniel D.
Publicado em 2011

Conformational Selection in a Protein-Protein Interaction revealed by Dynamic Pathway Analysis

Por Chakrabarti, Kalyan S., Agafonov, Roman V., Pontiggia, Francesco, Otten, Renee, Higgins, Matthew K., Schertler, Gebhard F. X., Oprian, Daniel D., Kern, Dorothee
Publicado no Cell Rep (2015)

Purification and Characterization of RhoPDE, a Retinylidene/Phosphodiesterase Fusion Protein and Potential Optogenetic Tool from the Choanoflagellate Salpingoeca rosetta

Por Lamarche, Lindsey B., Kumar, Ramasamy P., Trieu, Melissa M., Devine, Erin L., Cohen-Abeles, Luke E., Theobald, Douglas L., Oprian, Daniel D.
Publicado no Biochemistry (2017)

Expression, purification, and spectral tuning of RhoGC, a retinylidene/guanylyl cyclase fusion protein and optogenetics tool from the aquatic fungus Blastocladiella emersonii

Por Trieu, Melissa M., Devine, Erin L., Lamarche, Lindsey B., Ammerman, Aaron E., Greco, Jordan A., Birge, Robert R., Theobald, Douglas L., Oprian, Daniel D.
Publicado no J Biol Chem (2017)