Expression, purification, and spectral tuning of RhoGC, a retinylidene/guanylyl cyclase fusion protein and optogenetics tool from the aquatic fungus Blastocladiella emersonii

RhoGC is a rhodopsin (Rho)-guanylyl cyclase (GC) gene fusion molecule that is central to zoospore phototaxis in the aquatic fungus Blastocladiella emersonii. It has generated considerable excitement because of its demonstrated potential as a tool for optogenetic manipulation of cell-signaling pathwa...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Trieu, Melissa M., Devine, Erin L., Lamarche, Lindsey B., Ammerman, Aaron E., Greco, Jordan A., Birge, Robert R., Theobald, Douglas L., Oprian, Daniel D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2017
Ämnen:
Signal Transduction
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481551/
https://ncbi.nlm.nih.gov/pubmed/28473465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.789636
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