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Structure and monomer/dimer equilibrium for the guanylyl cyclase domain of the optogenetics protein RhoGC

RhoGC is a fusion protein from the aquatic fungus Blastocladiella emersonii, combining a type I rhodopsin domain with a guanylyl cyclase domain. It has generated excitement as an optogenetics tool for the manipulation of cyclic nucleotide signaling pathways. To investigate the regulation of the cycl...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Kumar, Ramasamy P., Morehouse, Benjamin R., Fofana, Josiane, Trieu, Melissa M., Zhou, Daniel H., Lorenz, Molly O., Oprian, Daniel D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766957/
https://ncbi.nlm.nih.gov/pubmed/29118188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.812685
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