Dynamic Ligand Exchange in Soluble Guanylyl Cyclase (sGC): IMPLICATIONS FOR sGC REGULATION AND DESENSITIZATION

Accumulating evidence indicates that the functional properties of soluble guanylyl cyclase (sGC) are affected not only by the binding of NO but also by the NO:sGC ratio and a number of cellular factors, including GTP. In this study, we monitored the time-resolved transformations of sGC and sGC-NO co...

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Bibliografski detalji
Glavni autori: Tsai, Ah-Lim, Berka, Vladimir, Sharina, Iraida, Martin, Emil
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Enzymology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234846/
https://ncbi.nlm.nih.gov/pubmed/22009742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.290304
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