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Dynamic Ligand Exchange in Soluble Guanylyl Cyclase (sGC): IMPLICATIONS FOR sGC REGULATION AND DESENSITIZATION
Accumulating evidence indicates that the functional properties of soluble guanylyl cyclase (sGC) are affected not only by the binding of NO but also by the NO:sGC ratio and a number of cellular factors, including GTP. In this study, we monitored the time-resolved transformations of sGC and sGC-NO co...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3234846/ https://ncbi.nlm.nih.gov/pubmed/22009742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.290304 |
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