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A constitutively activated mutant of human soluble guanylyl cyclase (sGC): Implication for the mechanism of sGC activation

Heterodimeric αβ soluble guanylyl cyclase (sGC) is a recognized receptor for nitric oxide (NO) and mediates many of its physiological functions. Although it has been clear that the heme moiety coordinated by His-105 of the β subunit is crucial for mediating the activation of the enzyme by NO, it is...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Martin, Emil, Sharina, Iraida, Kots, Alexander, Murad, Ferid
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC170897/
https://ncbi.nlm.nih.gov/pubmed/12883009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1633590100
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