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α1 Soluble Guanylyl Cyclase (sGC) Splice Forms as Potential Regulators of Human sGC Activity

Soluble guanylyl cyclase (sGC), a key protein in the NO/cGMP signaling pathway, is an obligatory heterodimeric protein composed of one α- and one β-subunit. The α(1)/β(1) sGC heterodimer is the predominant form expressed in various tissues and is regarded as the major isoform mediating NO-dependent...

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Main Authors: Sharina, Iraida G., Jelen, Filip, Bogatenkova, Elena P., Thomas, Anthony, Martin, Emil, Murad, Ferid
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397486/
https://ncbi.nlm.nih.gov/pubmed/18381288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710269200
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