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Dynamic Ligand Exchange in Soluble Guanylyl Cyclase (sGC): IMPLICATIONS FOR sGC REGULATION AND DESENSITIZATION

Accumulating evidence indicates that the functional properties of soluble guanylyl cyclase (sGC) are affected not only by the binding of NO but also by the NO:sGC ratio and a number of cellular factors, including GTP. In this study, we monitored the time-resolved transformations of sGC and sGC-NO co...

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Autori principali: Tsai, Ah-Lim, Berka, Vladimir, Sharina, Iraida, Martin, Emil
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234846/
https://ncbi.nlm.nih.gov/pubmed/22009742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.290304
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