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Structural origins of constitutive activation in rhodopsin: Role of the K296/E113 salt bridge
The intramolecular interactions that stabilize the inactive conformation of rhodopsin are of primary importance in elucidating the mechanism of activation of this and other G protein-coupled receptors. In the present study, site-directed spin labeling is used to explore the role of a buried salt bri...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC515088/ https://ncbi.nlm.nih.gov/pubmed/15306683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404519101 |
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