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Structural origins of constitutive activation in rhodopsin: Role of the K296/E113 salt bridge

The intramolecular interactions that stabilize the inactive conformation of rhodopsin are of primary importance in elucidating the mechanism of activation of this and other G protein-coupled receptors. In the present study, site-directed spin labeling is used to explore the role of a buried salt bri...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kim, Jong-Myoung, Altenbach, Christian, Kono, Masahiro, Oprian, Daniel D., Hubbell, Wayne L., Khorana, H. Gobind
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC515088/
https://ncbi.nlm.nih.gov/pubmed/15306683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404519101
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