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The Roles of Transmembrane Domain Helix-III during Rhodopsin Photoactivation

BACKGROUND: Rhodopsin, the prototypic member of G protein-coupled receptors (GPCRs), undergoes isomerization of 11-cis-retinal to all-trans-retinal upon photoactivation. Although the basic mechanism by which rhodopsin is activated is well understood, the roles of whole transmembrane (TM) helix-III d...

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Detalles Bibliográficos
Main Authors: Ou, Wen-bin, Yi, Tingfang, Kim, Jong-Myoung, Khorana, H. Gobind
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3045455/
https://ncbi.nlm.nih.gov/pubmed/21364764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017398
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