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Relocating the active-site lysine in rhodopsin and implications for evolution of retinylidene proteins

Type I and type II rhodopsins share several structural features including a G protein-coupled receptor fold and a highly conserved active-site Lys residue in the seventh transmembrane segment of the protein. However, the two families lack significant sequence similarity that would indicate common an...

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Bibliografische gegevens
Hoofdauteurs: Devine, Erin L., Oprian, Daniel D., Theobald, Douglas L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746867/
https://ncbi.nlm.nih.gov/pubmed/23904486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306826110
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