Crystal twinning of human MD-2 recognizing endotoxin cores of lipopolysaccharide

od Ohto, Umeharu, Satow, Yoshinori
Izdano 2008

Structural aspects of nucleic acid-sensing Toll-like receptors

od Ohto, Umeharu, Shimizu, Toshiyuki
izdano v Biophys Rev (2016)

Structure of human Roquin-2 and its complex with constitutive-decay element RNA

od Sakurai, Shunya, Ohto, Umeharu, Shimizu, Toshiyuki
izdano v Acta Crystallogr F Struct Biol Commun (2015)

The crystal structure of the AhRR–ARNT heterodimer reveals the structural basis of the repression of AhR-mediated transcription

od Sakurai, Shunya, Shimizu, Toshiyuki, Ohto, Umeharu
izdano v J Biol Chem (2017)

Crystal structure of the FYCO1 RUN domain suggests possible interfaces with small GTPases

od Sakurai, Shunya, Shimizu, Toshiyuki, Ohto, Umeharu
izdano v Acta Crystallogr F Struct Biol Commun (2020)

Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2

od Ohto, Umeharu, Fukase, Koichi, Miyake, Kensuke, Shimizu, Toshiyuki
Izdano 2012

The crystal structure of mouse LC3B in complex with the FYCO1 LIR reveals the importance of the flanking region of the LIR motif

od Sakurai, Shunya, Tomita, Taisuke, Shimizu, Toshiyuki, Ohto, Umeharu
izdano v Acta Crystallogr F Struct Biol Commun (2017)

The crystal structure of human DEAH-box RNA helicase 15 reveals a domain organization of the mammalian DEAH/RHA family

od Murakami, Karin, Nakano, Kenji, Shimizu, Toshiyuki, Ohto, Umeharu
izdano v Acta Crystallogr F Struct Biol Commun (2017)

Expression, purification, crystallization and preliminary X-ray crystallographic analysis of human β-galactosidase

od Usui, Kimihito, Ohto, Umeharu, Ochi, Toshinari, Shimizu, Toshiyuki, Satow, Yoshinori
Izdano 2011

Crystal structure of NOD2 and its implications in human disease

od Maekawa, Sakiko, Ohto, Umeharu, Shibata, Takuma, Miyake, Kensuke, Shimizu, Toshiyuki
izdano v Nat Commun (2016)

Structural Analyses of Human Toll-like Receptor 4 Polymorphisms D299G and T399I

od Ohto, Umeharu, Yamakawa, Natsuko, Akashi-Takamura, Sachiko, Miyake, Kensuke, Shimizu, Toshiyuki
Izdano 2012

Crystal Structure of Human β-Galactosidase: STRUCTURAL BASIS OF G(M1) GANGLIOSIDOSIS AND MORQUIO B DISEASES

od Ohto, Umeharu, Usui, Kimihito, Ochi, Toshinari, Yuki, Kenjiro, Satow, Yoshinori, Shimizu, Toshiyuki
Izdano 2012

Autoinhibition and relief mechanism by the proteolytic processing of Toll-like receptor 8

od Tanji, Hiromi, Ohto, Umeharu, Motoi, Yuji, Shibata, Takuma, Miyake, Kensuke, Shimizu, Toshiyuki
izdano v Proc Natl Acad Sci U S A (2016)

Structures of the SEp22 dodecamer, a Dps-like protein from Salmonella enterica subsp. enterica serovar Enteritidis

od Miyamoto, Takanori, Asahina, Yasuko, Miyazaki, Shohei, Shimizu, Hidetoshi, Ohto, Umeharu, Noguchi, Shuji, Satow, Yoshinori
Izdano 2010

Volatile anesthetics isoflurane and sevoflurane directly target and attenuate Toll-like receptor 4 system

od Okuno, Toshiaki, Koutsogiannaki, Sophia, Hou, Lifei, Bu, Weiming, Ohto, Umeharu, Eckenhoff, Roderic G., Yokomizo, Takehiko, Yuki, Koichi
izdano v FASEB J (2019)

The effect of anesthetics on toll like receptor 9

od Koutsogiannaki, Sophia, Bu, Weiming, Hou, Lifei, Shibamura-Fujiogi, Miho, Ishida, Hanako, Ohto, Umeharu, Eckenhoff, Roderic G., Yuki, Koichi
izdano v FASEB J (2020)

Structure-based Ligand Design of Novel Human Toll-like Receptor 8 Agonists

od Kokatla, Hari Prasad, Sil, Diptesh, Tanji, Hiromi, Ohto, Umeharu, Malladi, Subbalakshmi S., Fox, Lauren M., Shimizu, Toshiyoki, David, Sunil A.
Izdano 2014

Structural analysis of HTL and D14 proteins reveals the basis for ligand selectivity in Striga

od Xu, Yuqun, Miyakawa, Takuya, Nosaki, Shohei, Nakamura, Akira, Lyu, Ying, Nakamura, Hidemitsu, Ohto, Umeharu, Ishida, Hanako, Shimizu, Toshiyuki, Asami, Tadao, Tanokura, Masaru
izdano v Nat Commun (2018)

Small-molecule TLR8 antagonists via structure-based rational design

od Hu, Zhenyi, Tanji, Hiromi, Jiang, Shuangshuang, Zhang, Shuting, Koo, Kyoin, Chan, Jean, Sakaniwa, Kentaro, Ohto, Umeharu, Candia, Albert, Shimizu, Toshiyuki, Yin, Hang
izdano v Cell Chem Biol (2018)

Structure-Based Design of Human TLR8-Specific Agonists with Augmented Potency and Adjuvanticity

od Beesu, Mallesh, Caruso, Giuseppe, Salyer, Alex C. D., Khetani, Karishma K., Sil, Diptesh, Weerasinghe, Mihiri, Tanji, Hiromi, Ohto, Umeharu, Shimizu, Toshiyuki, David, Sunil A.
izdano v J Med Chem (2015)