Volatile anesthetics isoflurane and sevoflurane directly target and attenuate Toll-like receptor 4 system

General anesthesia has been the requisite component of surgical procedures for over 150 yr. Although immunomodulatory effects of volatile anesthetics have been growingly appreciated, the molecular mechanism has not been understood. In septic mice, the commonly used volatile anesthetic isoflurane att...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Okuno, Toshiaki, Koutsogiannaki, Sophia, Hou, Lifei, Bu, Weiming, Ohto, Umeharu, Eckenhoff, Roderic G., Yokomizo, Takehiko, Yuki, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894077/
https://ncbi.nlm.nih.gov/pubmed/31675483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901570R
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