Volatile anesthetics isoflurane and sevoflurane directly target and attenuate Toll-like receptor 4 system

General anesthesia has been the requisite component of surgical procedures for over 150 yr. Although immunomodulatory effects of volatile anesthetics have been growingly appreciated, the molecular mechanism has not been understood. In septic mice, the commonly used volatile anesthetic isoflurane att...

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Dades bibliogràfiques
Publicat a:FASEB J
Autors principals: Okuno, Toshiaki, Koutsogiannaki, Sophia, Hou, Lifei, Bu, Weiming, Ohto, Umeharu, Eckenhoff, Roderic G., Yokomizo, Takehiko, Yuki, Koichi
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894077/
https://ncbi.nlm.nih.gov/pubmed/31675483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901570R
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