Volatile anesthetics isoflurane and sevoflurane directly target and attenuate Toll-like receptor 4 system

General anesthesia has been the requisite component of surgical procedures for over 150 yr. Although immunomodulatory effects of volatile anesthetics have been growingly appreciated, the molecular mechanism has not been understood. In septic mice, the commonly used volatile anesthetic isoflurane att...

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Vydáno v:FASEB J
Hlavní autoři: Okuno, Toshiaki, Koutsogiannaki, Sophia, Hou, Lifei, Bu, Weiming, Ohto, Umeharu, Eckenhoff, Roderic G., Yokomizo, Takehiko, Yuki, Koichi
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894077/
https://ncbi.nlm.nih.gov/pubmed/31675483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901570R
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