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The crystal structure of the AhRR–ARNT heterodimer reveals the structural basis of the repression of AhR-mediated transcription

2,3,7,8-Tetrachlorodibenzo-p-dioxin and related compounds are extraordinarily potent environmental toxic pollutants. Most of the 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicities are mediated by aryl hydrocarbon receptor (AhR), a ligand-dependent transcription factor belonging to the basic helix-loop-h...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sakurai, Shunya, Shimizu, Toshiyuki, Ohto, Umeharu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663866/
https://ncbi.nlm.nih.gov/pubmed/28904176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.812974
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