Detailed molecular analysis of the induction of the L-PK gene by glucose

Por Eckert, David T., Zhang, Pili, Collier, J. Jason, O’Doherty, Robert M., Scott, Donald K.
Publicado em 2008

Similar degrees of obesity induced by diet or aging cause strikingly different immunologic and metabolic outcomes

Por Krishna, Kanthi B., Stefanovic‐Racic, Maja, Dedousis, Nikolaos, Sipula, Ian, O'Doherty, Robert M.
Publicado no Physiol Rep (2016)

Kupffer cells facilitate the acute effects of leptin on hepatic lipid metabolism

Por Metlakunta, Anantha, Huang, Wan, Stefanovic-Racic, Maja, Dedousis, Nikolaos, Sipula, Ian, O’Doherty, Robert M.
Publicado no Am J Physiol Endocrinol Metab (2017)

Leptin Augments the Acute Suppressive Effects of Insulin on Hepatic Very Low-Density Lipoprotein Production in Rats

Por Huang, Wan, Metlakunta, Anantha, Dedousis, Nikolas, Ortmeyer, Heidi K., Stefanovic-Racic, Maja, O'Doherty, Robert M.
Publicado em 2009

Mice Lacking NKT Cells but with a Complete Complement of CD8(+) T-Cells Are Not Protected against the Metabolic Abnormalities of Diet-Induced Obesity

Por Mantell, Benjamin S., Stefanovic-Racic, Maja, Yang, Xiao, Dedousis, Nikolas, Sipula, Ian J., O'Doherty, Robert M.
Publicado em 2011

c-Myc Is Required for the ChREBP-Dependent Activation of Glucose-Responsive Genes

Por Zhang, Pili, Metukuri, Mallikarjurna R., Bindom, Sharell M., Prochownik, Edward V., O'Doherty, Robert M., Scott, Donald K.
Publicado em 2010

Hepatocyte Growth Factor Is a Novel Stimulator of Glucose Uptake and Metabolism in Skeletal Muscle Cells

Por Perdomo, German, Martinez-Brocca, Maria A., Bhatt, Bankim A., Brown, Nicholas F., O'Doherty, Robert M., Garcia-Ocaña, Adolfo
Publicado em 2008

Activation of direct and indirect pathways of glycogen synthesis by hepatic overexpression of protein targeting to glycogen

Por O’Doherty, Robert M., Jensen, Per B., Anderson, Paul, Jones, John G., Berman, Hal K., Kearney, Denise, Newgard, Christopher B.
Publicado em 2000

Depletion of Liver Kupffer Cells Prevents the Development of Diet-Induced Hepatic Steatosis and Insulin Resistance

Por Huang, Wan, Metlakunta, Anantha, Dedousis, Nikolaos, Zhang, Pili, Sipula, Ian, Dube, John J., Scott, Donald K., O'Doherty, Robert M.
Publicado em 2010

Exercise Increases Mitochondrial Complex I Activity and DRP1 Expression in the Brains of Aged Mice

Por Gusdon, Aaron M., Callio, Jason, DiStefano, Giovanna, O’Doherty, Robert M., Goodpaster, Bret H., Coen, Paul M., Chu, Charleen T.
Publicado no Exp Gerontol (2017)

Notch intracellular domain overexpression in adipocytes confers lipodystrophy in mice

Por Chartoumpekis, Dionysios V., Palliyaguru, Dushani L., Wakabayashi, Nobunao, Khoo, Nicholas K.H., Schoiswohl, Gabriele, O'Doherty, Robert M., Kensler, Thomas W.
Publicado no Mol Metab (2015)

Acetylation of mitochondrial proteins by GCN5L1 promotes enhanced fatty acid oxidation in the heart

Por Thapa, Dharendra, Zhang, Manling, Manning, Janet R., Guimarães, Danielle A., Stoner, Michael W., O’Doherty, Robert M., Shiva, Sruti, Scott, Iain
Publicado no Am J Physiol Heart Circ Physiol (2017)

Hepatic Overexpression of Steroid Sulfatase Ameliorates Mouse Models of Obesity and Type 2 Diabetes through Sex-specific Mechanisms

Por Jiang, Mengxi, He, Jinhan, Kucera, Heidi, Gaikwad, Nilesh W., Zhang, Bin, Xu, Meishu, O'Doherty, Robert M., Selcer, Kyle W., Xie, Wen
Publicado em 2014

Intermittent Hypoxia Causes Insulin Resistance in Lean Mice Independent of Autonomic Activity

Por Iiyori, Nao, Alonso, Laura C., Li, Jianguo, Sanders, Mark H., Garcia-Ocana, Adolfo, O'Doherty, Robert M., Polotsky, Vsevolod Y., O'Donnell, Christopher P.
Publicado em 2007

Intermittent hypoxia reverses the diurnal glucose rhythm and causes pancreatic β-cell replication in mice

Por Yokoe, Takuya, Alonso, Laura C, Romano, Lia C, Rosa, Taylor C, O'Doherty, Robert M, Garcia-Ocana, Adolfo, Minoguchi, Kenji, O'Donnell, Christopher P
Publicado em 2008

Mechanisms by which the thiazolidinedione troglitazone protects against sucrose‐induced hepatic fat accumulation and hyperinsulinaemia

Por Martins, Fátima O, Delgado, Teresa C, Viegas, Joana, Gaspar, Joana M, Scott, Donald K, O'Doherty, Robert M, Paula Macedo, M, Jones, John G
Publicado no Br J Pharmacol (2016)

Cardiac-specific leptin receptor deletion exacerbates ischaemic heart failure in mice

Por McGaffin, Kenneth R., Witham, William G., Yester, Keith A., Romano, Lia C., O'Doherty, Robert M., McTiernan, Charles F., O'Donnell, Christopher P.
Publicado em 2011

Antimicrobials: Strategies for targeting obesity and metabolic health?

Por Murphy, Eileen F., Clarke, Siobhan F., Marques, Tatiana M., Hill, Colin, Stanton, Catherine, Ross, R. Paul, O’Doherty, Robert M., Shanahan, Fergus, Cotter, Paul D.
Publicado em 2013

Whole body overexpression of PGC-1α has opposite effects on hepatic and muscle insulin sensitivity

Por Liang, Huiyun, Balas, Bogdan, Tantiwong, Puntip, Dube, John, Goodpaster, Bret H., O'Doherty, Robert M., DeFronzo, Ralph A., Richardson, Arlan, Musi, Nicolas, Ward, Walter F.
Publicado em 2009

Skeletal muscle as a regulator of the longevity protein, Klotho

Por Avin, Keith G., Coen, Paul M., Huang, Wan, Stolz, Donna B., Sowa, Gwendolyn A., Dubé, John J., Goodpaster, Bret H., O'Doherty, Robert M., Ambrosio, Fabrisia
Publicado em 2014