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Cardiac-specific leptin receptor deletion exacerbates ischaemic heart failure in mice

AIMS: The obesity-related adipokine, leptin, has multiple actions on peripheral organs, including the mitigation of adverse cardiovascular outcomes after myocardial infarction (MI). Although we recently demonstrated that leptin, its receptor, and downstream signalling are up-regulated in the heart a...

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Detalhes bibliográficos
Main Authors: McGaffin, Kenneth R., Witham, William G., Yester, Keith A., Romano, Lia C., O'Doherty, Robert M., McTiernan, Charles F., O'Donnell, Christopher P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002875/
https://ncbi.nlm.nih.gov/pubmed/20833647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvq288
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