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Leptin signaling in the failing and mechanically unloaded human heart

BACKGROUND: Elevated circulating leptin is present in human heart failure, and leptin deficiency is linked to worse outcomes in chronic ischemic injury. In the present observational study, we tested the hypothesis that cardiac leptin production and signaling are increased in the failing human heart,...

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Detalhes bibliográficos
Main Authors: McGaffin, Kenneth R., Moravec, Christine S., McTiernan, Charles F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780432/
https://ncbi.nlm.nih.gov/pubmed/19919993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.109.869909
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