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Markers of Autophagy Are Downregulated in Failing Human Heart after Mechanical Unloading

BACKGROUND: Autophagy is a molecular process that breaks down damaged cellular organelles and yields amino acids for de novo protein synthesis or energy provision. Mechanical unloading with a left ventricular assist device (LVAD) decreases the energy demand of the failing human heart. We tested the...

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Autores principales: Kassiotis, Christos, Ballal, Kalpana, Wellnitz, Kari, Vela, Deborah, Gong, Mei, Salazar, Rebecca, Frazier, O Howard, Taegtmeyer, Heinrich
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778323/
https://ncbi.nlm.nih.gov/pubmed/19752367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.842252
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