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Leptin signaling in the failing and mechanically unloaded human heart

BACKGROUND: Elevated circulating leptin is present in human heart failure, and leptin deficiency is linked to worse outcomes in chronic ischemic injury. In the present observational study, we tested the hypothesis that cardiac leptin production and signaling are increased in the failing human heart,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: McGaffin, Kenneth R., Moravec, Christine S., McTiernan, Charles F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780432/
https://ncbi.nlm.nih.gov/pubmed/19919993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.109.869909
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