Depletion of Liver Kupffer Cells Prevents the Development of Diet-Induced Hepatic Steatosis and Insulin Resistance

OBJECTIVE: Increased activity of the innate immune system has been implicated in the pathogenesis of the dyslipidemia and insulin resistance associated with obesity and type 2 diabetes. In this study, we addressed the potential role of Kupffer cells (liver-specific macrophages, KCs) in these metabol...

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Detalhes bibliográficos
Main Authors: Huang, Wan, Metlakunta, Anantha, Dedousis, Nikolaos, Zhang, Pili, Sipula, Ian, Dube, John J., Scott, Donald K., O'Doherty, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809951/
https://ncbi.nlm.nih.gov/pubmed/19934001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0016
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