Notch intracellular domain overexpression in adipocytes confers lipodystrophy in mice

OBJECTIVE: The Notch family of intermembrane receptors is highly conserved across species and is involved in cell fate and lineage control. Previous in vitro studies have shown that Notch may inhibit adipogenesis. Here we describe the role of Notch in adipose tissue by employing an in vivo murine mo...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Chartoumpekis, Dionysios V., Palliyaguru, Dushani L., Wakabayashi, Nobunao, Khoo, Nicholas K.H., Schoiswohl, Gabriele, O'Doherty, Robert M., Kensler, Thomas W.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481462/
https://ncbi.nlm.nih.gov/pubmed/26137442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2015.04.004
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