Notch intracellular domain overexpression in adipocytes confers lipodystrophy in mice

OBJECTIVE: The Notch family of intermembrane receptors is highly conserved across species and is involved in cell fate and lineage control. Previous in vitro studies have shown that Notch may inhibit adipogenesis. Here we describe the role of Notch in adipose tissue by employing an in vivo murine mo...

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Dades bibliogràfiques
Publicat a:Mol Metab
Autors principals: Chartoumpekis, Dionysios V., Palliyaguru, Dushani L., Wakabayashi, Nobunao, Khoo, Nicholas K.H., Schoiswohl, Gabriele, O'Doherty, Robert M., Kensler, Thomas W.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2015
Matèries:
Brief Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481462/
https://ncbi.nlm.nih.gov/pubmed/26137442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2015.04.004
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