Nrf2 prevents Notch-induced insulin resistance and tumorigenesis in mice

Insulin resistance is associated with increased incidence and enhanced progression of cancers. However, little is known about strategies that can effectively ameliorate insulin resistance and consequently halt cancer progression. Herein, we propose that the transcription factor Nrf2 (also known as N...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Chartoumpekis, Dionysios V., Yagishita, Yoko, Fazzari, Marco, Palliyaguru, Dushani L., Rao, Uma N.M., Zaravinos, Apostolos, Khoo, Nicholas K.H., Schopfer, Francisco J., Weiss, Kurt R., Michalopoulos, George K., Sipula, Ian, O’Doherty, Robert M., Kensler, Thomas W., Wakabayashi, Nobunao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922294/
https://ncbi.nlm.nih.gov/pubmed/29515034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.97735
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