Acetylation of mitochondrial proteins by GCN5L1 promotes enhanced fatty acid oxidation in the heart

Lysine acetylation is a reversible posttranslational modification and is particularly important in the regulation of mitochondrial metabolic enzymes. Acetylation uses acetyl-CoA derived from fuel metabolism as a cofactor, thereby linking nutrition to metabolic activity. In the present study, we inve...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Thapa, Dharendra, Zhang, Manling, Manning, Janet R., Guimarães, Danielle A., Stoner, Michael W., O’Doherty, Robert M., Shiva, Sruti, Scott, Iain
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582919/
https://ncbi.nlm.nih.gov/pubmed/28526709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00752.2016
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