Whole body overexpression of PGC-1α has opposite effects on hepatic and muscle insulin sensitivity

Type 2 diabetes is characterized by fasting hyperglycemia, secondary to hepatic insulin resistance and increased glucose production. Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a transcriptional coactivator that is thought to control adaptive responses to physiological st...

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Bibliografiske detaljer
Main Authors: Liang, Huiyun, Balas, Bogdan, Tantiwong, Puntip, Dube, John, Goodpaster, Bret H., O'Doherty, Robert M., DeFronzo, Ralph A., Richardson, Arlan, Musi, Nicolas, Ward, Walter F.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2009
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670619/
https://ncbi.nlm.nih.gov/pubmed/19208857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.90292.2008
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