DICER Inactivation Identifies Pancreatic β-Cell “Disallowed” Genes Targeted by MicroRNAs

par Martinez-Sanchez, Aida, Nguyen-Tu, Marie-Sophie, Rutter, Guy A.
Publié dans Mol Endocrinol (2015)

Transcription factor-7–like 2 (TCF7L2) gene acts downstream of the Lkb1/Stk11 kinase to control mTOR signaling, β cell growth, and insulin secretion

par Nguyen-Tu, Marie-Sophie, da Silva Xavier, Gabriela, Leclerc, Isabelle, Rutter, Guy A.
Publié dans J Biol Chem (2018)

Correction: Transcription factor-7–like 2 (TCF7L2) gene acts downstream of the Lkb1/Stk11 kinase to control mTOR signaling, β cell growth, and insulin secretion.

par Nguyen-Tu, Marie-Sophie, da Silva Xavier, Gabriela, Leclerc, Isabelle, Rutter, Guy A.
Publié dans J Biol Chem (2018)

Adipocyte-specific deletion of Tcf7l2 induces dysregulated lipid metabolism and impairs glucose tolerance in mice

par Nguyen-Tu, Marie-Sophie, Martinez-Sanchez, Aida, Leclerc, Isabelle, Rutter, Guy A., da Silva Xavier, Gabriela
Publié dans Diabetologia (2020)

Accuracy of GFR Estimation in Obese Patients

par Lemoine, Sandrine, Guebre-Egziabher, Fitsum, Sens, Florence, Nguyen-Tu, Marie-Sophie, Juillard, Laurent, Dubourg, Laurence, Hadj-Aissa, Aoumeur
Publié 2014

Inflammation-linked adaptations in dermal microvascular reactivity accompany the development of obesity and type 2 diabetes

par Nguyen-Tu, Marie-Sophie, Nivoit, Pierre, Oréa, Valérie, Lemoine, Sandrine, Acquaviva, Cécile, Pagnon-Minot, Aurélie, Fromy, Bérengère, Sethi, Jaswinder K., Sigaudo-Roussel, Dominique
Publié dans Int J Obes (Lond) (2018)

The transcription factor Pax6 is required for pancreatic β cell identity, glucose-regulated ATP synthesis, and Ca(2+) dynamics in adult mice

par Mitchell, Ryan K., Nguyen-Tu, Marie-Sophie, Chabosseau, Pauline, Callingham, Rebecca M., Pullen, Timothy J., Cheung, Rebecca, Leclerc, Isabelle, Hodson, David J., Rutter, Guy A.
Publié dans J Biol Chem (2017)

Disallowance of Acot7 in β-cells is required for normal glucose tolerance and insulin secretion

par Martinez-Sanchez, Aida, Pullen, Timothy J., Chabosseau, Pauline, Zhang, Qifeng, Haythorne, Elizabeth, Cane, Matthew C., Nguyen-Tu, Marie-Sophie, Sayers, Sophie R., Rutter, Guy A.
Publié dans Diabetes (2016)

Remote control of glucose homeostasis in vivo using photopharmacology

par Mehta, Zenobia B., Johnston, Natalie R., Nguyen-Tu, Marie-Sophie, Broichhagen, Johannes, Schultz, Peter, Larner, Dean P., Leclerc, Isabelle, Trauner, Dirk, Rutter, Guy A., Hodson, David J.
Publié dans Sci Rep (2017)

Hypothalamic arcuate nucleus glucokinase regulates insulin secretion and glucose homeostasis

par Ma, Yue, Ratnasabapathy, Risheka, Izzi‐Engbeaya, Chioma, Nguyen‐Tu, Marie‐Sophie, Richardson, Errol, Hussain, Sufyan, De Backer, Ivan, Holton, Christopher, Norton, Mariana, Carrat, Gaelle, Schwappach, Blanche, Rutter, Guy A., Dhillo, Waljit S., Gardiner, James
Publié dans Diabetes Obes Metab (2018)

Glucose in the hypothalamic paraventricular nucleus regulates GLP-1 release

par Ma, Yue, Ratnasabapathy, Risheka, De Backer, Ivan, Izzi-Engbeaya, Chioma, Nguyen-Tu, Marie-Sophie, Cuenco, Joyceline, Jones, Ben, John, Christopher D., Lam, Brian Y.H., Rutter, Guy A., Yeo, Giles S.H., Dhillo, Waljit S., Gardiner, James
Publié dans JCI Insight (2020)

MiR-184 expression is regulated by AMPK in pancreatic islets

par Martinez-Sanchez, Aida, Nguyen-Tu, Marie-Sophie, Cebola, Ines, Yavari, Arash, Marchetti, Piero, Piemonti, Lorenzo, de Koning, Eelco, Shapiro, A. M. James, Johnson, Paul, Sakamoto, Kei, Smith, David M., Leclerc, Isabelle, Ashrafian, Houman, Ferrer, Jorge, Rutter, Guy A.
Publié dans FASEB J (2018)

LKB1 and AMPK differentially regulate pancreatic β-cell identity

par Kone, Marina, Pullen, Timothy J., Sun, Gao, Ibberson, Mark, Martinez-Sanchez, Aida, Sayers, Sophie, Nguyen-Tu, Marie-Sophie, Kantor, Chase, Swisa, Avital, Dor, Yuval, Gorman, Tracy, Ferrer, Jorge, Thorens, Bernard, Reimann, Frank, Gribble, Fiona, McGinty, James A., Chen, Lingling, French, Paul M., Birzele, Fabian, Hildebrandt, Tobias, Uphues, Ingo, Rutter, Guy A.
Publié dans FASEB J (2014)

Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice

par Carrat, Gaelle R., Hu, Ming, Nguyen-Tu, Marie-Sophie, Chabosseau, Pauline, Gaulton, Kyle J., van de Bunt, Martijn, Siddiq, Afshan, Falchi, Mario, Thurner, Matthias, Canouil, Mickaël, Pattou, Francois, Leclerc, Isabelle, Pullen, Timothy J., Cane, Matthew C., Prabhala, Priyanka, Greenwald, William, Schulte, Anke, Marchetti, Piero, Ibberson, Mark, MacDonald, Patrick E., Manning Fox, Jocelyn E., Gloyn, Anna L., Froguel, Philippe, Solimena, Michele, McCarthy, Mark I., Rutter, Guy A.
Publié dans Am J Hum Genet (2017)

Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function

par Yavari, Arash, Stocker, Claire J., Ghaffari, Sahar, Wargent, Edward T., Steeples, Violetta, Czibik, Gabor, Pinter, Katalin, Bellahcene, Mohamed, Woods, Angela, Martínez de Morentin, Pablo B., Cansell, Céline, Lam, Brian Y.H., Chuster, André, Petkevicius, Kasparas, Nguyen-Tu, Marie-Sophie, Martinez-Sanchez, Aida, Pullen, Timothy J., Oliver, Peter L., Stockenhuber, Alexander, Nguyen, Chinh, Lazdam, Merzaka, O’Dowd, Jacqueline F., Harikumar, Parvathy, Tóth, Mónika, Beall, Craig, Kyriakou, Theodosios, Parnis, Julia, Sarma, Dhruv, Katritsis, George, Wortmann, Diana D.J., Harper, Andrew R., Brown, Laurence A., Willows, Robin, Gandra, Silvia, Poncio, Victor, de Oliveira Figueiredo, Márcio J., Qi, Nathan R., Peirson, Stuart N., McCrimmon, Rory J., Gereben, Balázs, Tretter, László, Fekete, Csaba, Redwood, Charles, Yeo, Giles S.H., Heisler, Lora K., Rutter, Guy A., Smith, Mark A., Withers, Dominic J., Carling, David, Sternick, Eduardo B., Arch, Jonathan R.S., Cawthorne, Michael A., Watkins, Hugh, Ashrafian, Houman
Publié dans Cell Metab (2016)