The two pore channel TPC2 is dispensable in pancreatic β-cells for normal Ca(2+) dynamics and insulin secretion

Por Cane, Matthew C., Parrington, John, Rorsman, Patrik, Galione, Antony, Rutter, Guy A.
Publicado no Cell Calcium (2016)

Molecular Genetic Regulation of Slc30a8/ZnT8 Reveals a Positive Association With Glucose Tolerance

Por Mitchell, Ryan K., Hu, Ming, Chabosseau, Pauline L., Cane, Matthew C., Meur, Gargi, Bellomo, Elisa A., Carzaniga, Raffaella, Collinson, Lucy M., Li, Wen-Hong, Hodson, David J., Rutter, Guy A.
Publicado no Mol Endocrinol (2016)

Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β-cell are associated with glucose intolerance in humans and mice

Por Mehta, Zenobia B., Fine, Nicholas, Pullen, Timothy J., Cane, Matthew C., Hu, Ming, Chabosseau, Pauline, Meur, Gargi, Velayos-Baeza, Antonio, Monaco, Anthony P., Marselli, Lorella, Marchetti, Piero, Rutter, Guy A.
Publicado no Am J Physiol Endocrinol Metab (2016)

Incretin-Modulated Beta Cell Energetics in Intact Islets of Langerhans

Por Hodson, David J., Tarasov, Andrei I., Gimeno Brias, Silvia, Mitchell, Ryan K., Johnston, Natalie R., Haghollahi, Shahab, Cane, Matthew C., Bugliani, Marco, Marchetti, Piero, Bosco, Domenico, Johnson, Paul R., Hughes, Stephen J., Rutter, Guy A.
Publicado em 2014

Caffeine protects against experimental acute pancreatitis by inhibition of inositol 1,4,5-trisphosphate receptor-mediated Ca(2+) release

Por Huang, Wei, Cane, Matthew C, Mukherjee, Rajarshi, Szatmary, Peter, Zhang, Xiaoying, Elliott, Victoria, Ouyang, Yulin, Chvanov, Michael, Latawiec, Diane, Wen, Li, Booth, David M, Haynes, Andrea C, Petersen, Ole H, Tepikin, Alexei V, Criddle, David N, Sutton, Robert
Publicado no Gut (2017)

Fatty acid ethyl ester synthase inhibition ameliorates ethanol-induced Ca(2+)-dependent mitochondrial dysfunction and acute pancreatitis

Por Huang, Wei, Booth, David M, Cane, Matthew C, Chvanov, Michael, Javed, Muhammad A, Elliott, Victoria L, Armstrong, Jane A, Dingsdale, Hayley, Cash, Nicole, Li, Yan, Greenhalf, William, Mukherjee, Rajarshi, Kaphalia, Bhupendra S, Jaffar, Mohammed, Petersen, Ole H, Tepikin, Alexei V, Sutton, Robert, Criddle, David N
Publicado em 2014

Mechanism of mitochondrial permeability transition pore induction and damage in the pancreas: inhibition prevents acute pancreatitis by protecting production of ATP

Por Mukherjee, Rajarshi, Mareninova, Olga A, Odinokova, Irina V, Huang, Wei, Murphy, John, Chvanov, Michael, Javed, Muhammad A, Wen, Li, Booth, David M, Cane, Matthew C, Awais, Muhammad, Gavillet, Bruno, Pruss, Rebecca M, Schaller, Sophie, Molkentin, Jeffery D, Tepikin, Alexei V, Petersen, Ole H, Pandol, Stephen J, Gukovsky, Ilya, Criddle, David N, Gukovskaya, Anna S, Sutton, Robert
Publicado no Gut (2016)

Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice

Por Carrat, Gaelle R., Hu, Ming, Nguyen-Tu, Marie-Sophie, Chabosseau, Pauline, Gaulton, Kyle J., van de Bunt, Martijn, Siddiq, Afshan, Falchi, Mario, Thurner, Matthias, Canouil, Mickaël, Pattou, Francois, Leclerc, Isabelle, Pullen, Timothy J., Cane, Matthew C., Prabhala, Priyanka, Greenwald, William, Schulte, Anke, Marchetti, Piero, Ibberson, Mark, MacDonald, Patrick E., Manning Fox, Jocelyn E., Gloyn, Anna L., Froguel, Philippe, Solimena, Michele, McCarthy, Mark I., Rutter, Guy A.
Publicado no Am J Hum Genet (2017)