Optical control of GPR40 signalling in pancreatic β-cells

Por Frank, James Allen, Yushchenko, Dmytro A., Fine, Nicholas H. F., Duca, Margherita, Citir, Mevlut, Broichhagen, Johannes, Hodson, David J., Schultz, Carsten, Trauner, Dirk
Publicado no Chem Sci (2017)

Optical control of a receptor-linked guanylyl cyclase using a photoswitchable peptidic hormone

Por Podewin, Tom, Broichhagen, Johannes, Frost, Christina, Groneberg, Dieter, Ast, Julia, Meyer-Berg, Helena, Fine, Nicholas H. F., Friebe, Andreas, Zacharias, Martin, Hodson, David J., Trauner, Dirk, Hoffmann-Röder, Anja
Publicado no Chem Sci (2017)

Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β-cell are associated with glucose intolerance in humans and mice

Por Mehta, Zenobia B., Fine, Nicholas, Pullen, Timothy J., Cane, Matthew C., Hu, Ming, Chabosseau, Pauline, Meur, Gargi, Velayos-Baeza, Antonio, Monaco, Anthony P., Marselli, Lorella, Marchetti, Piero, Rutter, Guy A.
Publicado no Am J Physiol Endocrinol Metab (2016)

Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion

Por Fine, Nicholas H.F., Doig, Craig L., Elhassan, Yasir S., Vierra, Nicholas C., Marchetti, Piero, Bugliani, Marco, Nano, Rita, Piemonti, Lorenzo, Rutter, Guy A., Jacobson, David A., Lavery, Gareth G., Hodson, David J.
Publicado no Diabetes (2018)

Dimerization of the Sodium/Iodide Symporter

Por Thompson, Rebecca J., Fletcher, Alice, Brookes, Katie, Nieto, Hannah, Alshahrani, Mohammed M., Mueller, Jonathan W., Fine, Nicholas H.F., Hodson, David J., Boelaert, Kristien, Read, Martin L., Smith, Vicki E., McCabe, Christopher J.
Publicado no Thyroid (2019)

AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1‐Parkin independent manner

Por Seabright, Alex P., Fine, Nicholas H. F., Barlow, Jonathan P., Lord, Samuel O., Musa, Ibrahim, Gray, Alexander, Bryant, Jack A., Banzhaf, Manuel, Lavery, Gareth G., Hardie, D. Grahame, Hodson, David J., Philp, Andrew, Lai, Yu‐Chiang
Publicado no FASEB J (2020)

Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology

Por Podewin, Tom, Ast, Julia, Broichhagen, Johannes, Fine, Nicholas H. F., Nasteska, Daniela, Leippe, Philipp, Gailer, Manuel, Buenaventura, Teresa, Kanda, Nisha, Jones, Ben J., M’Kadmi, Celine, Baneres, Jean-Louis, Marie, Jacky, Tomas, Alejandra, Trauner, Dirk, Hoffmann-Röder, Anja, Hodson, David J.
Publicado no ACS Cent Sci (2018)

PDX1(LOW) MAFA(LOW) β-cells contribute to islet function and insulin release

Por Nasteska, Daniela, Fine, Nicholas H. F., Ashford, Fiona B., Cuozzo, Federica, Viloria, Katrina, Smith, Gabrielle, Dahir, Aisha, Dawson, Peter W. J., Lai, Yu-Chiang, Bastidas-Ponce, Aimée, Bakhti, Mostafa, Rutter, Guy A., Fiancette, Remi, Nano, Rita, Piemonti, Lorenzo, Lickert, Heiko, Zhou, Qiao, Akerman, Ildem, Hodson, David J.
Publicado no Nat Commun (2021)

Structure-functional changes in eNAMPT at high concentrations mediate mouse and human beta cell dysfunction in type 2 diabetes

Por Sayers, Sophie R., Beavil, Rebecca L., Fine, Nicholas H. F., Huang, Guo C., Choudhary, Pratik, Pacholarz, Kamila J., Barran, Perdita E., Butterworth, Sam, Mills, Charlotte E., Cruickshank, J. Kennedy, Silvestre, Marta P., Poppitt, Sally D., McGill, Anne-Thea, Lavery, Gareth G., Hodson, David J., Caton, Paul W.
Publicado no Diabetologia (2019)

Androgen excess in pancreatic β cells and neurons predisposes female mice to type 2 diabetes

Por Navarro, Guadalupe, Allard, Camille, Morford, Jamie J., Xu, Weiwei, Liu, Suhuan, Molinas, Adrien J.R., Butcher, Sierra M., Fine, Nicholas H.F., Blandino-Rosano, Manuel, Sure, Venkata N., Yu, Sangho, Zhang, Rui, Münzberg, Heike, Jacobson, David A., Katakam, Prasad V., Hodson, David J., Bernal-Mizrachi, Ernesto, Zsombok, Andrea, Mauvais-Jarvis, Franck
Publicado no JCI Insight (2018)

Vitamin-D-Binding Protein Contributes to the Maintenance of α Cell Function and Glucagon Secretion

Por Viloria, Katrina, Nasteska, Daniela, Briant, Linford J.B., Heising, Silke, Larner, Dean P., Fine, Nicholas H.F., Ashford, Fiona B., da Silva Xavier, Gabriela, Ramos, Maria Jiménez, Hasib, Annie, Cuozzo, Federica, Manning Fox, Jocelyn E., MacDonald, Patrick E., Akerman, Ildem, Lavery, Gareth G., Flaxman, Christine, Morgan, Noel G., Richardson, Sarah J., Hewison, Martin, Hodson, David J.
Publicado no Cell Rep (2020)

Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics

Por Ast, Julia, Arvaniti, Anastasia, Fine, Nicholas H. F., Nasteska, Daniela, Ashford, Fiona B., Stamataki, Zania, Koszegi, Zsombor, Bacon, Andrea, Jones, Ben J., Lucey, Maria A., Sasaki, Shugo, Brierley, Daniel I., Hastoy, Benoit, Tomas, Alejandra, D’Agostino, Giuseppe, Reimann, Frank, Lynn, Francis C., Reissaus, Christopher A., Linnemann, Amelia K., D’Este, Elisa, Calebiro, Davide, Trapp, Stefan, Johnsson, Kai, Podewin, Tom, Broichhagen, Johannes, Hodson, David J.
Publicado no Nat Commun (2020)

Author Correction: Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics

Por Ast, Julia, Arvaniti, Anastasia, Fine, Nicholas H. F., Nasteska, Daniela, Ashford, Fiona B., Stamataki, Zania, Koszegi, Zsombor, Bacon, Andrea, Jones, Ben J., Lucey, Maria A., Sasaki, Shugo, Brierley, Daniel I., Hastoy, Benoit, Tomas, Alejandra, D’Agostino, Giuseppe, Reimann, Frank, Lynn, Francis C., Reissaus, Christopher A., Linnemann, Amelia K., D’Este, Elisa, Calebiro, Davide, Trapp, Stefan, Johnsson, Kai, Podewin, Tom, Broichhagen, Johannes, Hodson, David J.
Publicado no Nat Commun (2020)

Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis

Por Mousavy Gharavy, S. Neda, Owen, Bryn M., Millership, Steven J., Chabosseau, Pauline, Pizza, Grazia, Martinez-Sanchez, Aida, Tasoez, Emirhan, Georgiadou, Eleni, Hu, Ming, Fine, Nicholas H. F., Jacobson, David A., Dickerson, Matthew T., Idevall-Hagren, Olof, Montoya, Alex, Kramer, Holger, Mehta, Zenobia, Withers, Dominic J., Ninov, Nikolay, Gadue, Paul J., Cardenas-Diaz, Fabian L., Cruciani-Guglielmacci, Céline, Magnan, Christophe, Ibberson, Mark, Leclerc, Isabelle, Voz, Marianne, Rutter, Guy A.
Publicado no Diabetologia (2021)