Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics

The glucagon-like peptide-1 receptor (GLP1R) is a class B G protein-coupled receptor (GPCR) involved in metabolism. Presently, its visualization is limited to genetic manipulation, antibody detection or the use of probes that stimulate receptor activation. Herein, we present LUXendin645, a far-red f...

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Publicado no:Nat Commun
Main Authors: Ast, Julia, Arvaniti, Anastasia, Fine, Nicholas H. F., Nasteska, Daniela, Ashford, Fiona B., Stamataki, Zania, Koszegi, Zsombor, Bacon, Andrea, Jones, Ben J., Lucey, Maria A., Sasaki, Shugo, Brierley, Daniel I., Hastoy, Benoit, Tomas, Alejandra, D’Agostino, Giuseppe, Reimann, Frank, Lynn, Francis C., Reissaus, Christopher A., Linnemann, Amelia K., D’Este, Elisa, Calebiro, Davide, Trapp, Stefan, Johnsson, Kai, Podewin, Tom, Broichhagen, Johannes, Hodson, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981144/
https://ncbi.nlm.nih.gov/pubmed/31980626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14309-w
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