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Disallowance of Acot7 in β-cells is required for normal glucose tolerance and insulin secretion
Acot7, encoding acyl-CoA thioesterase-7, is one of ~60 genes expressed ubiquitously across tissues but relatively silenced, or “disallowed”, in pancreatic β-cells. The capacity of ACOT7 to hydrolyse long-chain acyl-CoA esters suggests potential roles in β-oxidation, lipid biosynthesis, signal transd...
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| Pubblicato in: | Diabetes |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6101210/ https://ncbi.nlm.nih.gov/pubmed/26861785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-1240 |
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