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Disallowance of Acot7 in β-cells is required for normal glucose tolerance and insulin secretion

Acot7, encoding acyl-CoA thioesterase-7, is one of ~60 genes expressed ubiquitously across tissues but relatively silenced, or “disallowed”, in pancreatic β-cells. The capacity of ACOT7 to hydrolyse long-chain acyl-CoA esters suggests potential roles in β-oxidation, lipid biosynthesis, signal transd...

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書目詳細資料
發表在:Diabetes
Main Authors: Martinez-Sanchez, Aida, Pullen, Timothy J., Chabosseau, Pauline, Zhang, Qifeng, Haythorne, Elizabeth, Cane, Matthew C., Nguyen-Tu, Marie-Sophie, Sayers, Sophie R., Rutter, Guy A.
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101210/
https://ncbi.nlm.nih.gov/pubmed/26861785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-1240
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