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DICER Inactivation Identifies Pancreatic β-Cell “Disallowed” Genes Targeted by MicroRNAs

Pancreatic β-cells are the body's sole source of circulating insulin and essential for the maintenance of blood glucose homeostasis. Levels of up to 66 “disallowed” genes, which are strongly expressed and play housekeeping roles in most other mammalian tissues, are unusually low in β-cells. The...

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Vydáno v:Mol Endocrinol
Hlavní autoři: Martinez-Sanchez, Aida, Nguyen-Tu, Marie-Sophie, Rutter, Guy A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484783/
https://ncbi.nlm.nih.gov/pubmed/26038943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1059
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