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Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis

Posttranscriptional gene regulation by microRNAs (miRNAs) is important for many aspects of development, homeostasis, and disease. Here, we show that reduction of endothelial miRNAs by cell-specific inactivation of Dicer, the terminal endonuclease responsible for the generation of miRNAs, reduces pos...

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Detalhes bibliográficos
Main Authors: Suárez, Yajaira, Fernández-Hernando, Carlos, Yu, Jun, Gerber, Scott A., Harrison, Kenneth D., Pober, Jordan S., Iruela-Arispe, M. Luisa, Merkenschlager, Matthias, Sessa, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2544582/
https://ncbi.nlm.nih.gov/pubmed/18779589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804597105
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