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DICER Inactivation Identifies Pancreatic β-Cell “Disallowed” Genes Targeted by MicroRNAs

Pancreatic β-cells are the body's sole source of circulating insulin and essential for the maintenance of blood glucose homeostasis. Levels of up to 66 “disallowed” genes, which are strongly expressed and play housekeeping roles in most other mammalian tissues, are unusually low in β-cells. The...

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Bibliografske podrobnosti
izdano v:Mol Endocrinol
Main Authors: Martinez-Sanchez, Aida, Nguyen-Tu, Marie-Sophie, Rutter, Guy A.
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484783/
https://ncbi.nlm.nih.gov/pubmed/26038943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1059
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