Increased osteopontin expression in dendritic cells amplifies IL-17 production by CD4(+) T cells in experimental autoimmune encephalomyelitis and in multiple sclerosis

Por Murugaiyan, Gopal, Mittal, Akanksha, Weiner, Howard L.
Publicado em 2008

Identification of an IL-27/osteopontin axis in dendritic cells and its modulation by IFN-γ limits IL-17–mediated autoimmune inflammation

Por Murugaiyan, Gopal, Mittal, Akanksha, Weiner, Howard L.
Publicado em 2010

MicroRNA-21, T helper lineage and autoimmunity

Por Murugaiyan, Gopal, Garo, Lucien P., Weiner, Howard L.
Publicado no Oncotarget (2015)

Silencing MicroRNA-155 Ameliorates Experimental Autoimmune Encephalomyelitis

Por Murugaiyan, Gopal, Beynon, Vanessa, Mittal, Akanksha, Joller, Nicole, Weiner, Howard L.
Publicado em 2011

IFN-γ limits Th9 mediated autoimmune inflammation through dendritic cell modulation of IL-27

Por Murugaiyan, Gopal, Beynon, Vanessa, da Cunha, Andre Pires, Joller, Nicole, Weiner, Howard L.
Publicado em 2012

Increased IL-23 secretion and altered chemokine production by dendritic cells upon CD46 activation in patients with multiple sclerosis

Por Vaknin-Dembinsky, Adi, Murugaiyan, Gopal, Hafler, David A., Astier, Anne L., Weiner, Howard L.
Publicado em 2008

IL-27 Is a Key Regulator of IL-10 and IL-17 Production by Human CD4(+) T Cells

Por Murugaiyan, Gopal, Mittal, Akanksha, Lopez-Diego, Rocio, Maier, Lisa M., Anderson, David E., Weiner, Howard L.
Publicado em 2009

An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis

Por Quintana, Francisco J., Murugaiyan, Gopal, Farez, Mauricio F., Mitsdoerffer, Meike, Tukpah, Ann-Marcia, Burns, Evan J., Weiner, Howard L.
Publicado em 2010

Induction of regulatory T cells decreases adipose inflammation and alleviates insulin resistance in ob/ob mice

Por Ilan, Yaron, Maron, Ruth, Tukpah, Ann-Marcia, Maioli, Tatiani Uceli, Murugaiyan, Gopal, Yang, Kaiyong, Wu, Henry Yim, Weiner, Howard L.
Publicado em 2010

Metallothioneins negatively regulate IL-27–induced type 1 regulatory T-cell differentiation

Por Wu, Chuan, Pot, Caroline, Apetoh, Lionel, Thalhamer, Theresa, Zhu, Bing, Murugaiyan, Gopal, Xiao, Sheng, Lee, Youjin, Rangachari, Manu, Yosef, Nir, Kuchroo, Vijay K.
Publicado em 2013

MicroRNA-21 promotes Th17 differentiation and mediates experimental autoimmune encephalomyelitis

Por Murugaiyan, Gopal, da Cunha, Andre Pires, Ajay, Amrendra K., Joller, Nicole, Garo, Lucien P., Kumaradevan, Sowmiya, Yosef, Nir, Vaidya, Vishal S., Weiner, Howard L.
Publicado no J Clin Invest (2015)

AHR activation is protective against colitis driven by T cells in humanized mice

Por Goettel, Jeremy A., Gandhi, Roopali, Kenison, Jessica E., Yeste, Ada, Murugaiyan, Gopal, Sambanthamoorthy, Sharmila, Griffith, Alexandra E., Patel, Bonny, Shouval, Dror S., Weiner, Howard L., Snapper, Scott B., Quintana, Francisco J.
Publicado no Cell Rep (2016)

Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS

Por Butovsky, Oleg, Siddiqui, Shafiuddin, Gabriely, Galina, Lanser, Amanda J., Dake, Ben, Murugaiyan, Gopal, Doykan, Camille E., Wu, Pauline M., Gali, Reddy R., Iyer, Lakshmanan K., Lawson, Robert, Berry, James, Krichevsky, Anna M., Cudkowicz, Merit E., Weiner, Howard L.
Publicado em 2012

Identification of a novel mechanism of action of fingolimod (FTY720) on human effector T cell function through TCF-1 upregulation

Por Mazzola, Maria Antonietta, Raheja, Radhika, Murugaiyan, Gopal, Rajabi, Hasan, Kumar, Deepak, Pertel, Thomas, Regev, Keren, Griffin, Russell, Aly, Lilian, Kivisakk, Pia, Nejad, Parham, Patel, Bonny, Gwanyalla, Nguendab, Hei, Hillary, Glanz, Bonnie, Chitnis, Tanuja, Weiner, Howard L., Gandhi, Roopali
Publicado no J Neuroinflammation (2015)

Melatonin Contributes To The Seasonality Of Multiple Sclerosis Relapses

Por Farez, Mauricio F., Mascanfroni, Ivan D., Méndez-Huergo, Santiago P., Yeste, Ada, Murugaiyan, Gopal, Garo, Lucien P., Balbuena Aguirre, María E., Patel, Bonny, Ysrraelit, María C., Zhu, Chen, Kuchroo, Vijay K., Rabinovich, Gabriel A., Quintana, Francisco J., Correale, Jorge
Publicado no Cell (2015)

Targeting latency-associated peptide promotes anti-tumor immunity

Por Gabriely, Galina, da Cunha, Andre P., Rezende, Rafael M., Kenyon, Brendan, Madi, Asaf, Vandeventer, Tyler, Skillin, Nathaniel, Rubino, Stephen, Garo, Lucien, Mazzola, Maria A., Kolypetri, Panagiota, Lanser, Amanda J., Moreira, Thais, Faria, Ana Maria C., Lassmann, Hans, Kuchroo, Vijay, Murugaiyan, Gopal, Weiner, Howard L.
Publicado no Sci Immunol (2017)

Oral Administration of OKT3 Monoclonal Antibody to Human Subjects Induces a Dose-Dependent Immunologic Effect in T Cells and Dendritic Cells

Por Ilan, Yaron, Zigmond, Ehud, Lalazar, Gadi, Dembinsky, Adi, Ya’acov, Ami Ben, Hemed, Nila, Kasis, Ibrahim, Axelrod, Elizabeth, Zolotarov, Lidya, Klein, Athalia, El Haj, Madi, Gandhi, Roopali, Baecher-Allan, Claire, Wu, Henry, Murugaiyan, Gopal, Kivisakk, Pia, Farez, Mauricio F., Quintana, Francisco J., Khoury, Samia J., Weiner, Howard L.
Publicado em 2009

Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice

Por Butovsky, Oleg, Jedrychowski, Mark P., Cialic, Ron, Krasemann, Susanne, Murugaiyan, Gopal, Fanek, Zain, Greco, David J., Wu, Pauline M., Doykan, Camille E., Kiner, Olga, Lawson, Robert J., Frosch, Matthew P., Pochet, Nathalie, Fatimy, Rachid El, Krichevsky, Anna M., Gygi, Steven P., Lassman, Hans, Berry, James, Cudkowicz, Merit E., Weiner, Howard L.
Publicado no Ann Neurol (2014)