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IL-27 Is a Key Regulator of IL-10 and IL-17 Production by Human CD4(+) T Cells

Although the physiologic pathways that control regulatory T cells (Foxp3-expressing regulatory T cells, IL-10-secreting Tr1 cells) and Th17 cells in rodents have been defined, the factors that control these differentiation pathways in humans are not well understood. In this study, we show that IL-27...

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Detalhes bibliográficos
Main Authors: Murugaiyan, Gopal, Mittal, Akanksha, Lopez-Diego, Rocio, Maier, Lisa M., Anderson, David E., Weiner, Howard L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904948/
https://ncbi.nlm.nih.gov/pubmed/19625647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900568
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