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IL-27 induction of IL-21 from human CD8(+) T cells induces granzyme B in an autocrine manner
Interleukin (IL)-27 exerts an anti-inflammatory effect on human and mice CD4(+) T cells by inducing IL-10-producing T regulatory 1 cells through induction of IL-21. However, the role of IL-27 and how it regulates IL-21 from human CD8(+) T cells is unclear. Here, we show that the IL-27 receptor is ex...
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| Udgivet i: | Immunol Cell Biol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7293547/ https://ncbi.nlm.nih.gov/pubmed/22430249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2012.14 |
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