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Increased osteopontin expression in dendritic cells amplifies IL-17 production by CD4(+) T cells in experimental autoimmune encephalomyelitis and in multiple sclerosis
Osteopontin (Opn) is a broadly expressed pleiotropic cytokine and has been shown to play an important role in various autoimmune diseases including multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE). It is reported that Opn exacerbates EAE by skewing T cell...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2653058/ https://ncbi.nlm.nih.gov/pubmed/19017937 |
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