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An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis

The ligand-activated transcription factor aryl hydrocarbon receptor (AHR) participates in the differentiation of FoxP3(+) T(reg), Tr1 cells, and IL-17–producing T cells (Th17). Most of our understanding on the role of AHR on the FoxP3(+) T(reg) compartment results from studies using the toxic synthe...

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Bibliografiske detaljer
Main Authors: Quintana, Francisco J., Murugaiyan, Gopal, Farez, Mauricio F., Mitsdoerffer, Meike, Tukpah, Ann-Marcia, Burns, Evan J., Weiner, Howard L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996442/
https://ncbi.nlm.nih.gov/pubmed/21068375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009201107
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