AHR activation is protective against colitis driven by T cells in humanized mice

Existing therapies for inflammatory bowel disease based on broad suppression of inflammation result in variable clinical benefit and unwanted side effects. A potential therapeutic approach for promoting immune tolerance is the in vivo induction of regulatory T cells (Tregs). Here we report that acti...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Goettel, Jeremy A., Gandhi, Roopali, Kenison, Jessica E., Yeste, Ada, Murugaiyan, Gopal, Sambanthamoorthy, Sharmila, Griffith, Alexandra E., Patel, Bonny, Shouval, Dror S., Weiner, Howard L., Snapper, Scott B., Quintana, Francisco J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5106873/
https://ncbi.nlm.nih.gov/pubmed/27783946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.09.082
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