AHR activation is protective against colitis driven by T cells in humanized mice

Existing therapies for inflammatory bowel disease based on broad suppression of inflammation result in variable clinical benefit and unwanted side effects. A potential therapeutic approach for promoting immune tolerance is the in vivo induction of regulatory T cells (Tregs). Here we report that acti...

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Vydáno v:Cell Rep
Hlavní autoři: Goettel, Jeremy A., Gandhi, Roopali, Kenison, Jessica E., Yeste, Ada, Murugaiyan, Gopal, Sambanthamoorthy, Sharmila, Griffith, Alexandra E., Patel, Bonny, Shouval, Dror S., Weiner, Howard L., Snapper, Scott B., Quintana, Francisco J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5106873/
https://ncbi.nlm.nih.gov/pubmed/27783946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.09.082
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