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Metabolic control of type 1 regulatory (Tr1) cell differentiation by AHR and HIF1-α

Our understanding of the pathways that regulate lymphocyte metabolism, as well as the effects of metabolism and its products on the immune response, is still limited. We report that a metabolic program controlled by the transcription factors hypoxia inducible factor-1α (HIF1-α) and aryl hydrocarbon...

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書誌詳細
出版年:Nat Med
主要な著者: Mascanfroni, Ivan D., Takenaka, Maisa C., Yeste, Ada, Patel, Bonny, Wu, Yan, Kenison, Jessica E., Siddiqui, Shafiuddin, Basso, Alexandre S., Otterbein, Leo E., Pardoll, Drew M., Pan, Fan, Priel, Avner, Clish, Clary B., Robson, Simon C., Quintana, Francisco J.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476246/
https://ncbi.nlm.nih.gov/pubmed/26005855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3868
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