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Metabolic control of type 1 regulatory (Tr1) cell differentiation by AHR and HIF1-α

Our understanding of the pathways that regulate lymphocyte metabolism, as well as the effects of metabolism and its products on the immune response, is still limited. We report that a metabolic program controlled by the transcription factors hypoxia inducible factor-1α (HIF1-α) and aryl hydrocarbon...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Nat Med
Main Authors: Mascanfroni, Ivan D., Takenaka, Maisa C., Yeste, Ada, Patel, Bonny, Wu, Yan, Kenison, Jessica E., Siddiqui, Shafiuddin, Basso, Alexandre S., Otterbein, Leo E., Pardoll, Drew M., Pan, Fan, Priel, Avner, Clish, Clary B., Robson, Simon C., Quintana, Francisco J.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4476246/
https://ncbi.nlm.nih.gov/pubmed/26005855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3868
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