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Role of AHR and HIF-1α in glioblastoma metabolism
Glioblastoma (GBM) progression is associated with metabolic remodeling in both glioma and immune cells, resulting in the use of aerobic glycolysis as the main source energy and biosynthetic molecules. The transcription factor HIF-1α drives this metabolic reorganization. Oxygen levels as well as othe...
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| Publicado no: | Trends Endocrinol Metab |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5438779/ https://ncbi.nlm.nih.gov/pubmed/28318896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2017.02.009 |
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