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HIF1α and metabolic reprogramming in inflammation

HIF1α is a common component of pathways involved in the control of cellular metabolism and has a role in regulating immune cell effector functions. Additionally, HIF1α is critical for the maturation of dendritic cells and for the activation of T cells. HIF1α is induced in LPS-activated macrophages,...

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Pubblicato in:J Clin Invest
Autori principali: Corcoran, Sarah E., O’Neill, Luke A.J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096812/
https://ncbi.nlm.nih.gov/pubmed/27571407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI84431
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