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Metabolic reprogramming in macrophages and dendritic cells in innate immunity

Activation of macrophages and dendritic cells (DCs) by pro-inflammatory stimuli causes them to undergo a metabolic switch towards glycolysis and away from oxidative phosphorylation (OXPHOS), similar to the Warburg effect in tumors. However, it is only recently that the mechanisms responsible for thi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Res
Hauptverfasser: Kelly, Beth, O'Neill, Luke AJ
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493277/
https://ncbi.nlm.nih.gov/pubmed/26045163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2015.68
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