MicroRNA-21 promotes Th17 differentiation and mediates experimental autoimmune encephalomyelitis

Accumulation of IL-17–producing Th17 cells is associated with the development of multiple autoimmune diseases; however, the contribution of microRNA (miRNA) pathways to the intrinsic control of Th17 development remains unclear. Here, we demonstrated that miR-21 expression is elevated in Th17 cells a...

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Vydáno v:J Clin Invest
Hlavní autoři: Murugaiyan, Gopal, da Cunha, Andre Pires, Ajay, Amrendra K., Joller, Nicole, Garo, Lucien P., Kumaradevan, Sowmiya, Yosef, Nir, Vaidya, Vishal S., Weiner, Howard L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362225/
https://ncbi.nlm.nih.gov/pubmed/25642768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74347
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