The effect of inhibitors of receptor internalization on the desensitization and resensitization of three G(s)-coupled receptor responses

por Mundell, Stuart J, Kelly, Eamonn
Publicado 1998

Enhanced expression of G protein-coupled receptor kinase 2 selectively increases the sensitivity of A(2A) adenosine receptors to agonist-induced desensitization

por Mundell, Stuart J, Luty, Jason S, Willets, Jon, Benovic, Jeffrey L, Kelly, Eamonn
Publicado 1998

ARF6-Dependent Regulation of P2Y Receptor Traffic and Function in Human Platelets

por Kanamarlapudi, Venkateswarlu, Owens, Sian E., Saha, Keya, Pope, Robert J., Mundell, Stuart J.
Publicado 2012

Thioredoxin Inhibitors Attenuate Platelet Function and Thrombus Formation

por Metcalfe, Clive, Ramasubramoni, Anjana, Pula, Giordano, Harper, Matthew T., Mundell, Stuart J., Coxon, Carmen H.
Publicado en PLoS One (2016)

Arrestin Scaffolds NHERF1 to the P2Y(12) Receptor to Regulate Receptor Internalization

por Nisar, Shaista P., Cunningham, Margaret, Saxena, Kunal, Pope, Robert J., Kelly, Eamonn, Mundell, Stuart J.
Publicado 2012

Inverse agonism at the P2Y(12) receptor and ENT1 transporter blockade contribute to platelet inhibition by ticagrelor

por Aungraheeta, Riyaad, Conibear, Alexandra, Butler, Mark, Kelly, Eamonn, Nylander, Sven, Mumford, Andrew, Mundell, Stuart J.
Publicado en Blood (2016)

An intact PDZ motif is essential for correct P2Y(12) purinoceptor traffic in human platelets

por Nisar, Shaista, Daly, Martina E., Federici, Augusto B., Artoni, Andrea, Mumford, Andrew D., Watson, Stephen P., Mundell, Stuart J.
Publicado 2011

The opioid receptor pharmacology of GSK1521498 compared to other ligands with differential effects on compulsive reward-related behaviours

por Kelly, Eamonn, Mundell, Stuart J., Sava, Anna, Roth, Adelheid L., Felici, Antonio, Maltby, Kay, Nathan, Pradeep J., Bullmore, Edward T., Henderson, Graeme
Publicado en Psychopharmacology (Berl) (2014)

RhoG Protein Regulates Platelet Granule Secretion and Thrombus Formation in Mice

por Goggs, Robert, Harper, Matthew T., Pope, Robert J., Savage, Joshua S., Williams, Christopher M., Mundell, Stuart J., Heesom, Kate J., Bass, Mark, Mellor, Harry, Poole, Alastair W.
Publicado 2013

A novel thromboxane A(2) receptor D304N variant that abrogates ligand binding in a patient with a bleeding diathesis

por Mumford, Andrew D., Dawood, Ban B., Daly, Martina E., Murden, Sherina L., Williams, Michael D., Protty, Majd B., Spalton, Jennifer C., Wheatley, Mark, Mundell, Stuart J., Watson, Steve P.
Publicado en Blood (2009)

Endomorphin-2: A Biased Agonist at the μ-Opioid Receptor

por Rivero, Guadalupe, Llorente, Javier, McPherson, Jamie, Cooke, Alex, Mundell, Stuart J., McArdle, Craig A., Rosethorne, Elizabeth M., Charlton, Steven J., Krasel, Cornelius, Bailey, Christopher P., Henderson, Graeme, Kelly, Eamonn
Publicado 2012

Diversity and Impact of Rare Variants in Genes Encoding the Platelet G Protein-Coupled Receptors

por Jones, Matthew L., Norman, Jane E., Morgan, Neil V., Mundell, Stuart J., Lordkipanidzé, Marie, Lowe, Gillian C., Daly, Martina E., Simpson, Michael A., Drake, Sian, Watson, Steve P., Mumford, Andrew D.
Publicado en Thromb Haemost (2015)

Identification and Characterization of Novel Variations in Platelet G-Protein Coupled Receptor (GPCR) Genes in Patients Historically Diagnosed with Type 1 von Willebrand Disease

por Stockley, Jacqueline, Nisar, Shaista P., Leo, Vincenzo C., Sabi, Essa, Cunningham, Margaret R., Eikenboom, Jeroen C., Lethagen, Stefan, Schneppenheim, Reinhard, Goodeve, Anne C., Watson, Steve P., Mundell, Stuart J., Daly, Martina E.
Publicado en PLoS One (2015)

Pharmacodynamic Comparison of Ticagrelor Monotherapy Versus Ticagrelor and Aspirin in Patients After Percutaneous Coronary Intervention: The TEMPLATE (Ticagrelor Monotherapy and Pl...

por Johnson, Thomas W., Baos, Sarah, Collett, Laura, Hutchinson, James L., Nkau, Martin, Molina, Maria, Aungraheeta, Riyaad, Reilly‐Stitt, Christopher, Bowles, Ruth, Reeves, Barnaby C., Rogers, Chris A., Mundell, Stuart J, Baumbach, Andreas, Mumford, Andrew D.
Publicado en J Am Heart Assoc (2020)

Antiplatelet properties of Pim kinase inhibition are mediated through disruption of thromboxane A2 receptor signaling

por Unsworth, Amanda J., Bye, Alexander P., Sage, Tanya, Gaspar, Renato S., Eaton, Nathan, Drew, Caleb, Stainer, Alexander, Kriek, Neline, Volberding, Peter J., Hutchinson, James L., Riley, Ryan, Jones, Sarah, Mundell, Stuart J., Cui, Weiguo, Falet, Hervé, Gibbins, Jonathan M.
Publicado en Haematologica (2020)

Characterization of multiple platelet activation pathways in patients with bleeding as a high-throughput screening option: use of 96-well Optimul assay

por Lordkipanidzé, Marie, Lowe, Gillian C., Kirkby, Nicholas S., Chan, Melissa V., Lundberg, Martina H., Morgan, Neil V., Bem, Danai, Nisar, Shaista P., Leo, Vincenzo C., Jones, Matthew L., Mundell, Stuart J., Daly, Martina E., Mumford, Andrew D., Warner, Timothy D., Watson, Steve P.
Publicado 2014

Tetherin/BST2, a physiologically and therapeutically relevant regulator of platelet receptor signalling

por Zhao, Xiaojuan, Alibhai, Dominic, Sun, Ting, Khalil, Jawad, Hutchinson, James L., Olzak, Kaya, Williams, Christopher M., Li, Yong, Sessions, Richard, Cross, Stephen, Seager, Richard, Aungraheeta, Riyaad, Leard, Alan, McKinnon, Caroline M., Phillips, David, Zhang, Lei, Poole, Alastair W., Banting, George, Mundell, Stuart J.
Publicado en Blood Adv (2021)