Endomorphin-2: A Biased Agonist at the μ-Opioid Receptor

Previously we correlated the efficacy for G protein activation with that for arrestin recruitment for a number of agonists at the μ-opioid receptor (MOPr) stably expressed in HEK293 cells. We suggested that the endomorphins (endomorphin-1 and -2) might be biased toward arrestin recruitment. In the p...

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Detalhes bibliográficos
Main Authors: Rivero, Guadalupe, Llorente, Javier, McPherson, Jamie, Cooke, Alex, Mundell, Stuart J., McArdle, Craig A., Rosethorne, Elizabeth M., Charlton, Steven J., Krasel, Cornelius, Bailey, Christopher P., Henderson, Graeme, Kelly, Eamonn
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400840/
https://ncbi.nlm.nih.gov/pubmed/22553358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.078659
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